New Drugs in the Ulcerative Colitis Pipeline: Prometheus Unbound

New Biologic Drugs for Ulcerative Colitis

Inflammatory bowel diseases (IBD) are chronic remittent or progressive inflammatory conditions that may affect the gastrointestinal tract. Crohn’s disease (CD) and Ulcerative colitis (UC) are two main phenotypes of IBD. Their etiopathogenesis has not been elucidated but is thought to involve a complex interplay among genetic, environmental, microbial and immune response (1). In the last two dec...

Pulmonary function in ulcerative colitis

 Abstract Background: Pulmonary involvement in ulcerative colitis (UC) is thought to be rare. There is not a definite document about the question that "Is the lung a target organ in inflammatory bowel disease?" The aim of the present study is to compare lung function between cases with UC and healthy controls. This study will also be of interest about searching the outbreak of pulmonary functio...

SURGICAL TREATMENT OF ULCERATIVE COLITIS

This is a preliminary report of 28 patients with ulcerative colitis who we surgically treated with "J" pouch endorectal pull-through operation from 1978 to 1996. All patients are continent with a median stool frequency of 4 times per day, no night soilage. low postoperative complications and one mortality due to pulmonary embolism.

Ulcerative oesophagitis in association with ulcerative colitis.

Ulcerative colitis is primarily a disease of the large bowel, but a wide variety of extracolonic complications of the disease are now recognized (Edwards and Truelove, 1964), and a number of these occur in other parts of the alimentary tract. In the mouth, aphthous ulcers and monilial infections arise as a result of the general debility caused by the colitis (Grieve, 1964). Gastritis and small ...

Carcinogenesis in Ulcerative Colitis